Josh Tycko

Systematic discovery of protein functions in human cells to understand gene regulation and enable gene therapy



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Josh Tycko

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Department of Neurobiology

Harvard Medical School




Josh Tycko

Systematic discovery of protein functions in human cells to understand gene regulation and enable gene therapy



Department of Neurobiology

Harvard Medical School



Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements


Journal article


Josh Tycko*, M. Wainberg*, G. Marinov*, Oana Ursu, Gaelen T. Hess, Braeden K. Ego, Aradhana, Amy Li, Alisa N Truong, Alexandro E. Trevino, Kaitlyn K. Spees, David Yao, Irene M. Kaplow, P. Greenside, D. Morgens, D. Phanstiel, M. Snyder, Lacramioara Bintu, W. Greenleaf, A. Kundaje, M. Bassik
Nature Communications, 2019

Semantic Scholar DOI PubMedCentral PubMed
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APA   Click to copy
Tycko*, J., Wainberg*, M., Marinov*, G., Ursu, O., Hess, G. T., Ego, B. K., … Bassik, M. (2019). Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements. Nature Communications.


Chicago/Turabian   Click to copy
Tycko*, Josh, M. Wainberg*, G. Marinov*, Oana Ursu, Gaelen T. Hess, Braeden K. Ego, Aradhana, et al. “Mitigation of off-Target Toxicity in CRISPR-Cas9 Screens for Essential Non-Coding Elements.” Nature Communications (2019).


MLA   Click to copy
Tycko*, Josh, et al. “Mitigation of off-Target Toxicity in CRISPR-Cas9 Screens for Essential Non-Coding Elements.” Nature Communications, 2019.


BibTeX   Click to copy

@article{josh2019a,
  title = {Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements},
  year = {2019},
  journal = {Nature Communications},
  author = {Tycko*, Josh and Wainberg*, M. and Marinov*, G. and Ursu, Oana and Hess, Gaelen T. and Ego, Braeden K. and Aradhana and Li, Amy and Truong, Alisa N and Trevino, Alexandro E. and Spees, Kaitlyn K. and Yao, David and Kaplow, Irene M. and Greenside, P. and Morgens, D. and Phanstiel, D. and Snyder, M. and Bintu, Lacramioara and Greenleaf, W. and Kundaje, A. and Bassik, M.}
}


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