About

I develop new high-throughput, synthetic biology technologies to manipulate and measure human gene regulation.

I love taking systematic experimental approaches that enable progress towards a quantitative understanding of gene expression while keeping the door open for unexpected biological discoveries. Recently, we developed a new approach, HT-recruit, to measure how domains from all proteins in the human nucleus can affect gene expression when recruited to a target gene. We discovered transcriptional effector domains in 600 human proteins and shed new light on the evolution of major transcription factor families, like KRAB and Hox.

My long-term goal is to apply this knowledge to develop safe gene therapies that cure diseases. I have employed a variety of high-throughput methods to better measure, model, and mitigate CRISPR gene editing off-target activity, working in both academia and at a biotech startup.

I am currently working on my Ph.D. in the labs of Michael Bassik and Lacra Bintu with support from the NIH F99/K00 Fellowship.  At Stanford, I am a teaching assistant for a course on the science and bioethics of CRISPR, was an instructor for a hands-on cell engineering lab, and mentor our amazing iGEM team. As a BioFutures Fellow and co-leader of The Genetics Advocacy Committee, I collaborated with fellow trainees to critically analyze and improve graduate STEM training.

Please reach out if you would like to chat!